Effect of elasticity on wall shear stress inside cerebral aneurysm at anterior cerebral artery

Lijian Xu, Michiko Sugawara, Gaku Tanaka, Makoto Ohta, Hao Liu, Ryuhei Yamaguchi

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

BACKGROUND: Many numerical studies have been published with respect to about flow structures around cerebral aneurysm assuming to be rigid. Furthermore, there is little experimental research concerning aneurysm with elastic wall.Wall shear stress in elastic wall comparing with rigid wall should be clarified in experimental approach and verified in CFD. OBJECTIVE: We have experimentally realized elastic aneurysm model accompanying with wall deformation. Wall shear stress was examined for both rigid and elastic aneurysm models in pulsatile flow. METHODS: Effect of elasticity on wall shear stress inside aneurysm induced at the apex of anterior cerebral artery was experimentally examined by particle image velocimetry in vitro. In order to adjust the wall deformation, the pressure adjustment chamber was specially equipped outside the aneurysm wall. RESULTS: Effect of elasticity on wall shear stress was noticed on the comparison with that of rigidity. Wall elasticity reduced the peak magnitude, the spatial and temporal averaged wall shear stress comparing with those of wall rigidity experimentally. These reductions were endorsed by fluid-structure interaction simulation. CONCLUSION: Elastic wall comparing with rigid wall would reduce the peak magnitude, the spatial and temporal averaged wall shear stress acting on vascular wall.

Original languageEnglish
Pages (from-to)349-357
Number of pages9
JournalTechnology and Health Care
Volume24
Issue number3
DOIs
Publication statusPublished - 2016

Keywords

  • CFD
  • Cerebral aneurysm
  • PIV
  • elasticity
  • hemodynamics
  • wall shear stress

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Information Systems
  • Biomedical Engineering
  • Health Informatics

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