Effect of a notch at the distal end of a microcatheter on vein deformation in segmental adrenal venous sampling: a preliminary study using computational fluid dynamics

Tomo Kinoshita, Kazumasa Seiji, Narendra Kurnia Putra, Tomohito Watanabe, Sho Matsumoto, Makoto Ohta, Kei Takase

Research output: Contribution to journalArticle

Abstract

This study aimed to evaluate the effect of a notch at the distal end of a microcatheter on vein deformation in segmental adrenal venous sampling. A three-dimensional fluid–structure interaction simulation was performed using commercial finite element software. A computational model of a vein with a catheter inserted into it was constructed. The outer and inner diameters of the vein were 0.9 mm and 0.6 mm, respectively, whereas those of the catheter were 0.6 mm and 0.5 mm, respectively. The velocity of the blood flow at the outlet was 85 mm/s. The pressure at the inlet was 0 Pa. The mesh consisted of approximately 660,000 elements. The effect of the number (0–4) and shape (no notch, 1/4 circular, 1/3 circular, semicircular, 2/3 circlecircular, and 3/4 circular) of the notches at the distal end of the microcatheter on the vein deformation when a suction pressure was applied was evaluated. The venous wall displacement was the smallest with the one-notch catheter, followed by the four-notch catheter, and was the smallest with the catheter having 1/4-circular notches, followed by the one with 1/3-circular notches. In conclusion, microcatheters having one notch and 1/4-circular notches reduce vein deformation and lead to successful segmental adrenal venous sampling. [Figure not available: see fulltext.].

Original languageEnglish
JournalMedical and Biological Engineering and Computing
DOIs
Publication statusPublished - 2019 Jan 1

Keywords

  • Adrenal venous sampling
  • Adrenocortical adenoma
  • Catheter
  • Hydrodynamics
  • Vein deformation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

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