Ebpl expression is induced by influenza virus infection

Miho Ejima, Ryuta Ueda, Shinichiro Kume, Daisuke Okazaki, Takefumi Yamakawa, Hitoshi Shiku, Ayae Honda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Influenza virus PB1 protein plays the key role for the assembly and catalytic function of viral RNA polymerase. We showed that Ebpl interacted with PB1 and interfered both the viral RNA polymerase function in vitro and the virus growth. The Ebpl expression was induced by influenza virus infection using Western blotting and quantitative real time PCR assay. However, the quantitative determination has been requested of the relationship between influenza virus growth and Ebpl level. To analyze the relationship between virus growth and Ebpl level, we developed the assay system of single cell. Using this system, we confirmed the tight correlation between the Ebpl level and the influenza virus growth.

Original languageEnglish
Title of host publication2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics"
Pages214-218
Number of pages5
DOIs
Publication statusPublished - 2008 Dec 1
Event2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation" - Nagoya, Japan
Duration: 2008 Nov 62008 Nov 9

Publication series

Name2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008

Other

Other2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation"
CountryJapan
CityNagoya
Period08/11/608/11/9

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Human-Computer Interaction
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Ebpl expression is induced by influenza virus infection'. Together they form a unique fingerprint.

Cite this