Early death of mice cloned from somatic cells

Narumi Ogonuki, Kimiko Inoue, Yoshie Yamamoto, Yoko Noguchi, Kentaro Tanemura, Osamu Suzuki, Hiroyuki Nakayama, Kunio Doi, Yukiko Ohtomo, Michiko Satoh, Akira Nishida, Atsuo Ogura

Research output: Contribution to journalArticlepeer-review

208 Citations (Scopus)


Here we report that the lifespan of mice cloned from somatic cells is significantly shorter than that of genotype- and sex-matched controls, most likely due to severe pneumonia and hepatic failure. This finding demonstrates the possibility of long-term deleterious effects of somatic-cell cloning, even after normal birth.

Original languageEnglish
Pages (from-to)253-254
Number of pages2
JournalNature Genetics
Issue number3
Publication statusPublished - 2002 Mar
Externally publishedYes

ASJC Scopus subject areas

  • Genetics


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