Dysgenesis of corpus callosum with conjunctival malignant melanoma and iris nevus

Hisae Nishikatsu; Toshiaki Abe; Takuya Moriya; Eiichi Sato; Makoto Tamai

doi:10.1007/s12009-002-0030-8

Dysgenesis of corpus callosum with conjunctival malignant melanoma and iris nevus

Hisae Nishikatsu, Toshiaki Abe, Takuya Moriya, Eiichi Sato, Makoto Tamai

MED - United Centers for Advanced Research and Translational Medicine (ART)

Research output: Contribution to journal › Article › peer-review

Abstract

A 32-year-old man had dysgenesis of the corpus callosum associated with iris nevi and conjunctival malignant melanoma. Iris lesions revealed intrastromal proliferation of melanocytes accompanied by surface plaque. Epithelioid and spindle cells with pigmentation, positive for the melanoma marker HMB-45 and S-100 protein, were observed in the conjunctival lesion by histologic examination. These findings may suggest an underlying neoplastic potential of melanocytes.

Original language	English
Pages (from-to)	237-239
Number of pages	3
Journal	Annals of Ophthalmology
Volume	34
Issue number	3
DOIs	https://doi.org/10.1007/s12009-002-0030-8
Publication status	Published - 2002 Jan 1

ASJC Scopus subject areas

Ophthalmology

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abstract = "A 32-year-old man had dysgenesis of the corpus callosum associated with iris nevi and conjunctival malignant melanoma. Iris lesions revealed intrastromal proliferation of melanocytes accompanied by surface plaque. Epithelioid and spindle cells with pigmentation, positive for the melanoma marker HMB-45 and S-100 protein, were observed in the conjunctival lesion by histologic examination. These findings may suggest an underlying neoplastic potential of melanocytes.",

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AU - Sato, Eiichi

AU - Tamai, Makoto

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N2 - A 32-year-old man had dysgenesis of the corpus callosum associated with iris nevi and conjunctival malignant melanoma. Iris lesions revealed intrastromal proliferation of melanocytes accompanied by surface plaque. Epithelioid and spindle cells with pigmentation, positive for the melanoma marker HMB-45 and S-100 protein, were observed in the conjunctival lesion by histologic examination. These findings may suggest an underlying neoplastic potential of melanocytes.

AB - A 32-year-old man had dysgenesis of the corpus callosum associated with iris nevi and conjunctival malignant melanoma. Iris lesions revealed intrastromal proliferation of melanocytes accompanied by surface plaque. Epithelioid and spindle cells with pigmentation, positive for the melanoma marker HMB-45 and S-100 protein, were observed in the conjunctival lesion by histologic examination. These findings may suggest an underlying neoplastic potential of melanocytes.

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