Dual stimuli-responsive nanogels by self-assembly of polysaccharides lightly grafted with thiol-terminated poly(N-isopropylacrylamide) chains

Nobuyuki Morimoto; Xing Ping Qiu; Françoise M. Winnik; Kazunari Akiyoshi

doi:10.1021/ma801332x

Dual stimuli-responsive nanogels by self-assembly of polysaccharides lightly grafted with thiol-terminated poly(N-isopropylacrylamide) chains

Nobuyuki Morimoto, Xing Ping Qiu, Françoise M. Winnik, Kazunari Akiyoshi

Research output: Contribution to journal › Article › peer-review

106 Citations (Scopus)

Abstract

The preparation of nanogels by heat-induced association of polysaccharides grafted with short poly(N-isopropylacrylamide) (PNIPAM) chains was investigated. The nanogel building blocks were obtained by grafting short PNIPAM chains onto pollulan by reversible addition-fragmentation chain transfer (RAFT) polymerization of NIPAM in water controlled by sulfanythiocarbonylsulfanyl (STS) groups covalently attached to the pollulan, acting as chain transfer agents. Differential scanning calorimetry (DSC) revealed that aqueous solutions of all NgPuls undergo a phase transition upon heating with a transition temperature. The heat-induced collapse of the PNIPAM grafted chains induced significant changes. It was also observed that RAFT polymerization of PulSTS enables one to create various types of stimuli responsive nanomaterials.

Original language	English
Pages (from-to)	5985-5987
Number of pages	3
Journal	Macromolecules
Volume	41
Issue number	16
DOIs	https://doi.org/10.1021/ma801332x
Publication status	Published - 2008 Aug 26
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry
Polymers and Plastics
Inorganic Chemistry
Materials Chemistry

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10.1021/ma801332x

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title = "Dual stimuli-responsive nanogels by self-assembly of polysaccharides lightly grafted with thiol-terminated poly(N-isopropylacrylamide) chains",

abstract = "The preparation of nanogels by heat-induced association of polysaccharides grafted with short poly(N-isopropylacrylamide) (PNIPAM) chains was investigated. The nanogel building blocks were obtained by grafting short PNIPAM chains onto pollulan by reversible addition-fragmentation chain transfer (RAFT) polymerization of NIPAM in water controlled by sulfanythiocarbonylsulfanyl (STS) groups covalently attached to the pollulan, acting as chain transfer agents. Differential scanning calorimetry (DSC) revealed that aqueous solutions of all NgPuls undergo a phase transition upon heating with a transition temperature. The heat-induced collapse of the PNIPAM grafted chains induced significant changes. It was also observed that RAFT polymerization of PulSTS enables one to create various types of stimuli responsive nanomaterials.",

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AU - Morimoto, Nobuyuki

AU - Qiu, Xing Ping

AU - Winnik, Françoise M.

AU - Akiyoshi, Kazunari

PY - 2008/8/26

Y1 - 2008/8/26

N2 - The preparation of nanogels by heat-induced association of polysaccharides grafted with short poly(N-isopropylacrylamide) (PNIPAM) chains was investigated. The nanogel building blocks were obtained by grafting short PNIPAM chains onto pollulan by reversible addition-fragmentation chain transfer (RAFT) polymerization of NIPAM in water controlled by sulfanythiocarbonylsulfanyl (STS) groups covalently attached to the pollulan, acting as chain transfer agents. Differential scanning calorimetry (DSC) revealed that aqueous solutions of all NgPuls undergo a phase transition upon heating with a transition temperature. The heat-induced collapse of the PNIPAM grafted chains induced significant changes. It was also observed that RAFT polymerization of PulSTS enables one to create various types of stimuli responsive nanomaterials.

AB - The preparation of nanogels by heat-induced association of polysaccharides grafted with short poly(N-isopropylacrylamide) (PNIPAM) chains was investigated. The nanogel building blocks were obtained by grafting short PNIPAM chains onto pollulan by reversible addition-fragmentation chain transfer (RAFT) polymerization of NIPAM in water controlled by sulfanythiocarbonylsulfanyl (STS) groups covalently attached to the pollulan, acting as chain transfer agents. Differential scanning calorimetry (DSC) revealed that aqueous solutions of all NgPuls undergo a phase transition upon heating with a transition temperature. The heat-induced collapse of the PNIPAM grafted chains induced significant changes. It was also observed that RAFT polymerization of PulSTS enables one to create various types of stimuli responsive nanomaterials.

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Dual stimuli-responsive nanogels by self-assembly of polysaccharides lightly grafted with thiol-terminated poly(N-isopropylacrylamide) chains

Abstract

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