Dual stimuli-responsive nanogels by self-assembly of polysaccharides lightly grafted with thiol-terminated poly(N-isopropylacrylamide) chains

Nobuyuki Morimoto, Xing Ping Qiu, Françoise M. Winnik, Kazunari Akiyoshi

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

The preparation of nanogels by heat-induced association of polysaccharides grafted with short poly(N-isopropylacrylamide) (PNIPAM) chains was investigated. The nanogel building blocks were obtained by grafting short PNIPAM chains onto pollulan by reversible addition-fragmentation chain transfer (RAFT) polymerization of NIPAM in water controlled by sulfanythiocarbonylsulfanyl (STS) groups covalently attached to the pollulan, acting as chain transfer agents. Differential scanning calorimetry (DSC) revealed that aqueous solutions of all NgPuls undergo a phase transition upon heating with a transition temperature. The heat-induced collapse of the PNIPAM grafted chains induced significant changes. It was also observed that RAFT polymerization of PulSTS enables one to create various types of stimuli responsive nanomaterials.

Original languageEnglish
Pages (from-to)5985-5987
Number of pages3
JournalMacromolecules
Volume41
Issue number16
DOIs
Publication statusPublished - 2008 Aug 26
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

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