Dry and wet prolines for asymmetric organic solvent-free aldehyde-aldehyde and aldehyde-ketone aldol reactions

Yujiro Hayashi, Seiji Aratake, Takahiko Itoh, Tsubasa Okano, Tatsunobu Sumiya, Mitsuru Shoji

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

Dry and wet prolines were found to catalyze the direct aldol reactions of aldehyde-aldehyde and aldehyde-ketone, respectively, to afford aldols with excellent diastereo- and enantioselectivities, and an organic solvent-free reaction was realized in some cases.

Original languageEnglish
Pages (from-to)957-959
Number of pages3
JournalChemical Communications
Issue number9
DOIs
Publication statusPublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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