Downregulation of dullard expression enhances BMP-dependent neuritogenesis in PC12 cells

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The protein phosphatase dullard negatively regulates bone morphogenetic protein (BMP) signaling by promoting the dephosphorylation or degradation of BMP receptors. We investigated the effects of endogenous dullard downregulation on BMP-induced neuritogenesis in a rat PC12 cell line to assess the basic role of dullard in mammalian neuronal differentiation.

Original languageEnglish
Title of host publicationInterface Oral Health Science 2011
PublisherSpringer Japan
Pages167-169
Number of pages3
ISBN (Electronic)9784431540700
ISBN (Print)9784431540694
DOIs
Publication statusPublished - 2012 Jan 1

Keywords

  • Dullard
  • Neuronal differentiation
  • PC12
  • Phosphatase

ASJC Scopus subject areas

  • Dentistry(all)

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