Domino and one-pot syntheses of biologically active compounds using diphenylprolinol silyl ether

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Abstract

The successful application of diphenylprolinol silyl ether, which is one of the widely used organocatalysts, to the synthesis of natural products and drugs, is described mostly focusing on the author's results. The molecules that are explained in this paper are baclofen, telcagepant, oseltamivir, ABT-341, prostaglandins, estradiol, horsfiline and coerulescine.

Original languageEnglish
Article number20180088
JournalPhysical Sciences Reviews
Volume5
Issue number6
DOIs
Publication statusPublished - 2020 Jun 1

Keywords

  • diphenylprolinol silyl ether
  • enamine
  • iminium ion

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Physics and Astronomy(all)

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