DNA Origami Nanoplate-Based Emulsion with Nanopore Function

Daisuke Ishikawa, Yuki Suzuki, Chikako Kurokawa, Masayuki Ohara, Misato Tsuchiya, Masamune Morita, Miho Yanagisawa, Masayuki Endo, Ryuji Kawano, Masahiro Takinoue

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Bio-inspired functional microcapsules have attracted increasing attention in many fields from physical/chemical science to artificial-cell engineering. Although particle-stabilised microcapsules are advantageous for their stability and functionalisation potential, versatile methods for their functionalisation are desired to expand their possibilities. This study reports a water-in-oil microdroplet stabilised with amphiphilic DNA origami nanoplates. By utilising DNA nanotechnology, DNA nanoplates were designed as a nanopore device for ion transportation and to stabilise the oil–water interface. Microscopic examination revealed the microcapsule formed by the accumulation of amphiphilic DNA nanoplates at the oil–water interface. Ion current measurements revealed the nanoplate pores functioned as channel to transport ions. These findings provide a general strategy for the programmable design of microcapsules to engineer artificial cells and molecular robots.

Original languageEnglish
Pages (from-to)15299-15303
Number of pages5
JournalAngewandte Chemie - International Edition
Volume58
Issue number43
DOIs
Publication statusPublished - 2019 Oct 21

Keywords

  • DNA nanotechnology
  • Pickering emulsion
  • bio-inspired system
  • nanopore
  • self-assembly

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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