DNA-mimetics: Towards novel molecular devices having molecular information

M. Shimomura, R. Mitamura, J. Matsumoto, K. Ijiro

    Research output: Contribution to journalConference articlepeer-review

    14 Citations (Scopus)

    Abstract

    Two experimental methods for materialization of DNA as novel molecular devices are described. Two types of Langmuir monolayers complexed with DNA molecules at the air-water interface were prepared for single-DNA stretching and template polymerization of the DNA-mimetics, respectively. Single-DNA molecule can be stretched on the solid surface when the ionic complex of a double-stranded DNA and a cationic monolayer was transferred slowly from water surface to the hydrophilic solid surface by using conventional Langmuir-Blodgett technique. The surface monolayer of the diacetylene containing nucleobase amphiphiles prepared as DNA-mimetics can form complementary hydrogen bonds with single-stranded DNAs at the air-water interface. The single-stranded DNA molecule can act as a template of photopolymerization of the diacetylene groups in the DNA-mimetics. Combination of two methods will provide a new preparation strategy of single molecular devices based on DNA.

    Original languageEnglish
    Pages (from-to)473-475
    Number of pages3
    JournalSynthetic Metals
    Volume133-134
    DOIs
    Publication statusPublished - 2003 Mar 13
    EventISCOM 2001 - Rusutsu, Hokkaido, Japan
    Duration: 2001 Sep 102001 Sep 14

    Keywords

    • DNA
    • DNA-mimetics
    • Hydrogen bond
    • Langmuir monolayer
    • Polyion complex
    • Template polymerization

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Mechanics of Materials
    • Mechanical Engineering
    • Metals and Alloys
    • Materials Chemistry

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