TY - JOUR
T1 - Distribution of various calcium channel α1 subunits in murine DRG neurons and antinociceptive effect of ω-conotoxin SVIB in mice
AU - Murakami, Manabu
AU - Suzuki, Takashi
AU - Nakagawasai, Osamu
AU - Murakami, Hiroshi
AU - Murakami, Shinobu
AU - Esashi, Akihisa
AU - Taniguchi, Ryoo
AU - Yanagisawa, Teruyuki
AU - Tan-No, Koichi
AU - Miyoshi, Ichiro
AU - Sasano, Hironobu
AU - Tadano, Takeshi
N1 - Funding Information:
We thank Miss Kumiko Hidaka, Mrs Fumihiro Yamadera and Pei Xiang Yuan for technical assistance, and Drs Kensuke Kisara and Kazuo Nunoki, and Mr. Brent Bell for critically reading the manuscript. We also thank Dr Hidetoshi Shimauchi, Fuji Rebio Co. and Boehringer Ingelheim Co. for their help. This research was sponsored by grants-in-aid from the Ministry of Education, Science and Culture, Japan.
PY - 2001/6/8
Y1 - 2001/6/8
N2 - Immunohistological study revealed the differential localization of subtypes of voltage-dependent calcium channels in the dorsal root ganglion neurons. Intrathecal injection of ω-conotoxin SVIB, an analogue of ω-conotoxin GVIA, which acts on N-type voltage-dependent calcium channels, significantly shortened the licking time in the late phase of a formalin test.
AB - Immunohistological study revealed the differential localization of subtypes of voltage-dependent calcium channels in the dorsal root ganglion neurons. Intrathecal injection of ω-conotoxin SVIB, an analogue of ω-conotoxin GVIA, which acts on N-type voltage-dependent calcium channels, significantly shortened the licking time in the late phase of a formalin test.
KW - Calcium channel
KW - Nociception
KW - ω-Conotoxin SVIB
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U2 - 10.1016/S0006-8993(01)02427-1
DO - 10.1016/S0006-8993(01)02427-1
M3 - Article
C2 - 11382408
AN - SCOPUS:0035827094
VL - 903
SP - 231
EP - 236
JO - Molecular Brain Research
JF - Molecular Brain Research
SN - 0006-8993
IS - 1-2
ER -