Tetrodotoxin was detected in all nine species of newts tested, 6-epitetrodotoxin in six species, and 11-deoxytetrodotoxin in five species. Only one species lacked the analogues, thus suggesting that the analogues were common metabolites among newts. Toxin levels were high in Taricha granulosa and Notophthalmus viridescens followed by Cynops spp. Distinct differences in toxin contents and profiles existed among species and tissues.
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