Distinctive neurobehavioral features among neurodegenerative dementias

Nobutsugu Hirono, Etsuro Mori, Satoshi Tanimukai, Hiroaki Kazui, Mamoru Hashimoto, Tokiji Hanihara, Toru Imamura

Research output: Contribution to journalArticlepeer-review

69 Citations (Scopus)


The distinctive neuropsychiatric features of Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD) were investigated by using the Neuropsychiatric Inventory. The patients with FTD had significantly more euphoria, aberrant motor activity, and disinhibition and significantly fewer delusions compared with the patients with AD or DLB. The patients with DLB had significantly more hallucinations compared with the AD or FTD patients. The findings clearly demonstrate that AD, DLB, and FTD have distinctive neuropsychiatric features, which may correspond to different patterns of cerebral involvement characteristic of these three major degenerative dementias.

Original languageEnglish
Pages (from-to)498-503
Number of pages6
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number4
Publication statusPublished - 1999 Sep 1

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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