Distinct subpopulations of mechanosensory chordotonal organ neurons elicit grooming of the fruit fly antennae

Stefanie Hampel, Katharina Eichler, Daichi Yamada, Davi D. Bock, Azusa Kamikouchi, Andrew M. Seeds

Research output: Contribution to journalArticlepeer-review

Abstract

Diverse mechanosensory neurons detect different mechanical forces that can impact animal behavior. Yet our understanding of the anatomical and physiological diversity of these neurons and the behaviors that they influence is limited. We previously discovered that grooming of the Drosophila melanogaster antennae is elicited by an antennal mechanosensory chordotonal organ, the Johnston’s organ (JO) (Hampel et al., 2015). Here, we describe anatomically and physiologically distinct JO mechanosensory neuron subpopulations that each elicit antennal grooming. We show that the subpopulations project to different, discrete zones in the brain and differ in their responses to mechanical stimulation of the antennae. Although activation of each subpopulation elicits antennal grooming, distinct subpopulations also elicit the additional behaviors of wing flapping or backward locomotion. Our results provide a comprehensive description of the diversity of mechanosensory neurons in the JO, and reveal that distinct JO subpopulations can elicit both common and distinct behavioral responses.

Original languageEnglish
Article numbere59976
Pages (from-to)1-55
Number of pages55
JournaleLife
Volume9
DOIs
Publication statusPublished - 2020 Oct
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Immunology and Microbiology(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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