Discrimination ability and reproducibility of a new index reflecting autonomic nervous function based on pulsatile amplitude of photoplethysmography

Yusuke Kano, Makoto Yoshizawa, Norihiro Sugita, Makoto Abe, Noriyasu Homma, Akira Tanaka, Tsuyoshi Yamauchi, Hidekazu Miura, Yasuyuki Shiraishi, Tomoyuki Yambe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

A new physiological index (μPA) is proposed to represent the autonomic nervous system (ANS) function. The index μPA is defined as the natural logarithm of the ratio between two different frequency components of the pulsatile amplitude of the photoplethysmogram (PPG) signal. The discrimination ability and the reproducibility of μPA have been compared with other traditional ANS indices. In the experiment, the electrocardiogram, the PPG and continuous blood pressure were measured in 59 healthy young subjects (age 25.7 ± 6.3) and 86 healthy elderly subjects (age 70.2 ± 4.1) at rest. The discrimination ability and the reproducibility were evaluated by Cohen's d between young and elderly groups and by the interclass correlation coefficient, respectively. The results showed that the elderly subjects were significantly (p<0.001) lower than young subjects in μPA and a few traditional indices introduced to be compared with μPA. Therefore, it suggests that μPA is associated with the decrease in the ANS function accompanied by aging. Moreover, it showed that the discrimination ability and the reproducibility of the proposed index are comparable or larger than those of traditional indices. The proposed index based on the PPG signal will be applied to tele-healthcare systems for monitoring people's health in daily life in combination with the ratio of the standard deviation of the R-R intervals to their average value (CVRR).

Original languageEnglish
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1794-1800
Number of pages7
ISBN (Electronic)9781424479290
DOIs
Publication statusPublished - 2014 Nov 2
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: 2014 Aug 262014 Aug 30

Publication series

Name2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period14/8/2614/8/30

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering
  • Medicine(all)

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