Direct transformation of unprotected sugars to aryl 1-thio-β- glycosides in aqueous media using 2-chloro-l, 3-dimethylimidazolinium chloride

Tomonari Tanaka, Takeshi Matsumoto, Masato Noguchi, Atsushi Kobayashi, Shinichiro Shoda

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Aryl 1-thioglycosides have directly been synthesized in good yields from the corresponding unprotected sugars and thiols without protection of the hydroxy groups by using 2-chloro-l, 3-dimethylirnidazolinium chloride (DMC) as dehydrative condensing agent. The reaction proceeded in a mixed solvent of water and acetonitrile under mild reaction conditions, leading to the predominant formation of β-anomers.

Original languageEnglish
Pages (from-to)458-459
Number of pages2
JournalChemistry Letters
Volume38
Issue number5
DOIs
Publication statusPublished - 2009 Jul 20

ASJC Scopus subject areas

  • Chemistry(all)

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