Sugar oxazoline derivatives were directly prepared by dehydrative cyclization of 2-acetamido-2-deoxysugars using a water-soluble carbodiimide in water. N-Acetyl-D-glucosamine, N-acetyl-D-galactosamine, and N,N′-diacetylchitobiose were converted to the corresponding 1,2-oxazoline derivatives in 37, 28, and 40% yields, respectively.
|Number of pages||5|
|Publication status||Published - 2004 Jul 1|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry