Direct conversion of 2-acetamido-2-deoxysugars to 1,2-oxazoline derivatives by dehydrative cyclization in water

Jun Ichi Kadokawa, Mitsumasa Mito, Satoshi Takahashi, Masato Noguchi, Shin Ichiro Shoda

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Sugar oxazoline derivatives were directly prepared by dehydrative cyclization of 2-acetamido-2-deoxysugars using a water-soluble carbodiimide in water. N-Acetyl-D-glucosamine, N-acetyl-D-galactosamine, and N,N′-diacetylchitobiose were converted to the corresponding 1,2-oxazoline derivatives in 37, 28, and 40% yields, respectively.

Original languageEnglish
Pages (from-to)1531-1535
Number of pages5
JournalHeterocycles
Volume63
Issue number7
Publication statusPublished - 2004 Jul 1

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Direct conversion of 2-acetamido-2-deoxysugars to 1,2-oxazoline derivatives by dehydrative cyclization in water'. Together they form a unique fingerprint.

Cite this