Direct condensation of functionalized sp3 carbons with formanilides for enamine synthesis using an in situ generated HMDS amide catalyst

Hiroshi Taneda; Kiyofumi Inamoto; Yoshinori Kondo

doi:10.1039/c4cc02228a

Direct condensation of functionalized sp³ carbons with formanilides for enamine synthesis using an in situ generated HMDS amide catalyst

Hiroshi Taneda, Kiyofumi Inamoto, Yoshinori Kondo

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

The efficient synthesis of functionalized enamines including β-enaminoesters was effectively accomplished by the direct condensation of functionalized sp³ carbanions such as acetates with formamides using in situ generated HMDS base from catalytic cesium fluoride and stoichiometric tristrimethylsilylamine.

Original language	English
Pages (from-to)	6523-6525
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	49
DOIs	https://doi.org/10.1039/c4cc02228a
Publication status	Published - 2014 May 22

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c4cc02228a

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title = "Direct condensation of functionalized sp3 carbons with formanilides for enamine synthesis using an in situ generated HMDS amide catalyst",

abstract = "The efficient synthesis of functionalized enamines including β-enaminoesters was effectively accomplished by the direct condensation of functionalized sp3 carbanions such as acetates with formamides using in situ generated HMDS base from catalytic cesium fluoride and stoichiometric tristrimethylsilylamine.",

author = "Hiroshi Taneda and Kiyofumi Inamoto and Yoshinori Kondo",

year = "2014",

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AU - Taneda, Hiroshi

AU - Inamoto, Kiyofumi

AU - Kondo, Yoshinori

PY - 2014/5/22

Y1 - 2014/5/22

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AB - The efficient synthesis of functionalized enamines including β-enaminoesters was effectively accomplished by the direct condensation of functionalized sp3 carbanions such as acetates with formamides using in situ generated HMDS base from catalytic cesium fluoride and stoichiometric tristrimethylsilylamine.

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ER -

Direct condensation of functionalized sp³ carbons with formanilides for enamine synthesis using an in situ generated HMDS amide catalyst

Abstract

ASJC Scopus subject areas

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