Dilation of renal artery stenosis after administration of losartan

Masayuki Tanemoto, Kei Takase, Takayuki Yamada, Akihiro Satoh, Takaaki Abe, Sadayoshi Ito

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Transluminal angioplasty with a balloon catheter is effective to dilate renal artery stenosis (RAS) caused by fibromuscular dysplasia (FMD), but lesions resistant to the angioplasty exist. In this report, we describe the case of a young woman with RAS of FMD that was difficult to dilate even by cutting-balloon angioplasty. To facilitate the formation of a smooth intimal covering at the site of angioplasty, we administered losartan, an angiotensin receptor blocker, for 4 months after the angioplasty. Although re-stenosis was detected at 5 months after the angioplasty, the normotensive state continued without ant1hypertensives and the restenosis gradually dilated afterwards. The present case suggests the possibility of remodeling the renal artery during the normotensive state by administering losartan after the angioplasty.

Original languageEnglish
Pages (from-to)999-1002
Number of pages4
JournalHypertension Research
Volume30
Issue number10
DOIs
Publication statusPublished - 2007 Oct 1

Keywords

  • Angioplasty
  • Angiotensin
  • Fibromuscular dysplasia
  • Hypertension
  • Renal artery stenosis

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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