Dihydrodictyopyrones A and C: new members of dictyopyrone family isolated from Dictyostelium cellular slime molds

Haruhisa Kikuchi, Koji Nakamura, Yuzuru Kubohara, Naomi Gokan, Kohei Hosaka, Yasuo Maeda, Yoshiteru Oshima

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We have explored the diversity of secondary metabolites produced by cellular slime molds to evaluate if they are valuable resources for biologically potential substances. From the methanol extract of fruiting bodies of Dicyostelium firmibasis, we obtained new α-pyranoids, dihydrodictyopyrones A (1) and C (2). Their structures including absolute configurations were determined by spectral means and asymmetric total synthesis. Compounds 1 and 2 are new members of the dictyopyrone family, which are characteristic secondary metabolites of various species of Dictyostelium cellular slime molds.

Original languageEnglish
Pages (from-to)5905-5909
Number of pages5
JournalTetrahedron Letters
Volume48
Issue number33
DOIs
Publication statusPublished - 2007 Aug 13

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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