Digital recording and analysis of esophageal pressure for patients with obstructive sleep apnea-hypopnea syndrome

Masaaki Suzuki, Hiromasa Ogawa, Shinichi Okabe, Atsushi Horiuchi, Mau Okubo, Katsuhisa Ikeda, Wataru Hida, Toshimitsu Kobayashi

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

To evaluate sleep-related obstructive breathing events in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), we developed a technique for digital recording and analysis of esophageal pressure (Pes) and elucidated the Pes parameters. Pes was recorded overnight with a microtip-type pressure transducer in 74 patients with OSAHS. Simultaneously, in all patients digital polysomnography was recorded. The mean nadir end-apneic Pes swing (Pes Nadir) ranged from -20.2 to -147.4 cmH2O, with a mean of -53.6±2.9 cmH2 O. Correlation of the mean Pes Nadir indicated a linear relationship with the mean ratio of maximal Pes swing to apnea duration (r2 =0.70) and the mean area of the Pes (Pes Area) (r2=0.82). Significant correlations were noted between the mean Pes Nadir and apnea-hypopnea index (AHI, ranging from 7.9 to 109.5 per hour; r2=0.66), minimum SpO2 (r2=0.60), oxygen desaturation index (ODI) of more than 3 (r2=0.65), arousal index (r2=0.54), and between the mean Pes Area and AHI (r2=0.63), minimum percutaneous arterial oxygen saturation (SpO2; r2=0.57), ODI (r2 =0.69), and arousal index (r2=0.41). Pes parameters were found to be significant in the evaluation of the severity of the respiratory effort during the sleep-related obstructive breathing events for patients with OSAHS.

Original languageEnglish
Pages (from-to)64-72
Number of pages9
JournalSleep and Breathing
Volume9
Issue number2
DOIs
Publication statusPublished - 2005 Jun

Keywords

  • Esophageal pressure
  • Obstructive sleep apnea-hypopnea syndrome
  • Pleural pressure
  • Respiratory effort

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Clinical Neurology

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