Diffusion-weighted magnetic resonance imaging: Detection of ischemic injury 39 minutes after onset in a stroke patient

Yukihiro Yoneda, Keisuke Tokui, Tokiji Hanihara, Hajime Kitagaki, Masayasu Tabuchi, Etsuro Mori

Research output: Contribution to journalArticlepeer-review

67 Citations (Scopus)

Abstract

A neurologist witnessed the in-hospital onset of an ischemic stroke in a 71-year-old right-handed male who suddenly developed global aphasia and right hemiplegia. Diffusion-weighted magnetic resonance imaging (DWI) 39 minutes after the ictus demonstrated high signals in the left internal carotid artery territory. T1- and T2-weighted images failed to detect this change. Magnetic resonance angiography showed occlusions in branches of the left anterior and middle cerebral arteries and an atheromatous stenotic lesion in the ipsilateral proximal internal carotid artery. The patient was treated with intravenous heparin and low molecular dextran solution. Repeated magnetic resonance imagings identified an infarction slightly smaller than the abnormality demonstrated by the initial DWI. DWI detects hyperacute ischemic injury within 1 hour of symptom onset in human ischemic stroke.

Original languageEnglish
Pages (from-to)794-797
Number of pages4
JournalAnnals of Neurology
Volume45
Issue number6
DOIs
Publication statusPublished - 1999 Jun 15

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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