Diffuse bone marrow uptake on F-18 FDG PET in patients with myelodysplastic syndromes

Kentaro Inoue, Ken Okada, Hideo Harigae, Yasuyuki Taki, Ryoi Goto, Shigeo Kinomura, Shunsuke Kato, Tomohiro Kaneta, Hiroshi Fukuda

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


It is well known that hematopoietic cytokine stimulation can cause diffuse increase of FDG accumulation in bone marrow on PET imaging, which simulates that seen in patients with bone marrow metastases. However, diffuse bone marrow FDG uptake can be caused by other etiologies. We report 2 patients who did not have a history of hematopoietic cytokine stimulation. The FDG PET images showed diffuse bone marrow FDG uptake, and the patients were diagnosed as having myelodysplastic syndromes. These cases demonstrate that diffuse FDG uptake by bone marrow can suggest neoplastic disease of the hematopoietic tissues.

Original languageEnglish
Pages (from-to)721-723
Number of pages3
JournalClinical Nuclear Medicine
Issue number11
Publication statusPublished - 2006 Nov


  • Bone marrow
  • FDG
  • MDS
  • Myelodysplastic syndrome
  • PET

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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