Difficulty of the differential diagnosis of basal cell adenoma and basal cell adenocarcinoma of parotid gland by magnetic resonance imaging: Case reports and literature review

Ikuho Kojima, Maya Sakamoto, Mika Watanabe, Shoki Takahashi, Shunji Mugikura, Kiyoto Shiga, Masahiro Iikubo, Munemasa John Yamamura, Takashi Sasano

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Objectives: The aim of this study was to assess the efficacy of magnetic resonance imaging (MRI) for the differential diagnosis of basal cell adenocarcinoma (BCAC) and basal cell adenoma (BCA) in the salivary gland. Methods: Magnetic resonance imaging findings and pathological correlations were studied retrospectively in three cases of pathologically verified BCA and one case of BCAC. The MRI findings from previously reported cases (16 cases of BCA, 1 case of BCAC) were reviewed. Results: All three BCAs showed well-defined margins, a round or ovoid shape, homogeneous hypointense signal on T1-weighted imaging (T1WI), and moderate contrast enhancement on contrast-enhanced T1WI. T2-weighted imaging showed heterogeneous hyperintense signals in two cases and a hypointense signal in one. The BCAC displayed MRI findings similar to those of the BCAs, with histopathologically verified partial invasion into the surrounding tissue remaining undetected. Time-signal intensity curves on dynamic MRI displayed rapid enhancement followed by a low washout pattern in all BCA cases, and a gradual enhancement pattern in the BCAC case. Both of these patterns are nonspecific and are commonly seen in other salivary tumors. Conclusions: Both the BCAs and the BCAC showed nonspecific findings on MRI, making it difficult to distinguish between these entities, even with dynamic MRI.

Original languageEnglish
Pages (from-to)24-31
Number of pages8
JournalOral Radiology
Volume28
Issue number1
DOIs
Publication statusPublished - 2012 Mar

Keywords

  • Basal cell adenocarcinoma
  • Basal cell adenoma
  • Head and neck
  • Magnetic resonance imaging
  • Salivary gland neoplasms

ASJC Scopus subject areas

  • Dentistry (miscellaneous)
  • Radiology Nuclear Medicine and imaging

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