Two patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]Lmethionine (11C-Met). Case 1 showed high accumulation of11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with11C-Met seems to be useful for the differential diagnosis of solitary lung nodules.
- Contrast media
- Emission computed tomography
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging