Differential diagnosis of solitary pulmonary nodules with positron emission tomography using [11C]L-methionine

Kazuo Kubota, Taiju Matsuzawa, Takehiko Fujiwara, Yoshinao Abe, Masatoshi Ito, Jun Hatazawa, Tatsuo Ido, Kiichi Ishiwata, Seiichi Watanuki

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27 Citations (Scopus)

Abstract

Two patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]Lmethionine (11C-Met). Case 1 showed high accumulation of11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with11C-Met seems to be useful for the differential diagnosis of solitary lung nodules.

Original languageEnglish
Pages (from-to)794-796
Number of pages3
JournalJournal of Computer Assisted Tomography
Volume12
Issue number5
DOIs
Publication statusPublished - 1988 Sep

Keywords

  • Contrast media
  • Diseases
  • Emission computed tomography
  • Lungs
  • Lungs
  • Neoplasms

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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