Differential diagnosis of solitary pulmonary nodules with positron emission tomography using [11C]L-methionine

Kazuo Kubota; Taiju Matsuzawa; Takehiko Fujiwara; Yoshinao Abe; Masatoshi Ito; Jun Hatazawa; Tatsuo Ido; Kiichi Ishiwata; Seiichi Watanuki

doi:10.1097/00004728-198809010-00015

Differential diagnosis of solitary pulmonary nodules with positron emission tomography using [¹¹C]L-methionine

Kazuo Kubota, Taiju Matsuzawa, Takehiko Fujiwara, Yoshinao Abe, Masatoshi Ito, Jun Hatazawa, Tatsuo Ido, Kiichi Ishiwata, Seiichi Watanuki

Cyclotron and Radioisotope Center (CYRIC)

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Two patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [¹¹C-Methyl]Lmethionine (¹¹C-Met). Case 1 showed high accumulation of¹¹C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with¹¹C-Met seems to be useful for the differential diagnosis of solitary lung nodules.

Original language	English
Pages (from-to)	794-796
Number of pages	3
Journal	Journal of Computer Assisted Tomography
Volume	12
Issue number	5
DOIs	https://doi.org/10.1097/00004728-198809010-00015
Publication status	Published - 1988 Sep

Keywords

Contrast media
Diseases
Emission computed tomography
Lungs
Lungs
Neoplasms

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/00004728-198809010-00015

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Differential diagnosis of solitary pulmonary nodules with positron emission tomography using [¹¹C]L-methionine. / Kubota, Kazuo; Matsuzawa, Taiju; Fujiwara, Takehiko; Abe, Yoshinao; Ito, Masatoshi; Hatazawa, Jun; Ido, Tatsuo; Ishiwata, Kiichi; Watanuki, Seiichi.

In: Journal of Computer Assisted Tomography, Vol. 12, No. 5, 09.1988, p. 794-796.

Research output: Contribution to journal › Article › peer-review

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abstract = "Two patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]Lmethionine (11C-Met). Case 1 showed high accumulation of11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with11C-Met seems to be useful for the differential diagnosis of solitary lung nodules.",

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AU - Ito, Masatoshi

AU - Hatazawa, Jun

AU - Ido, Tatsuo

AU - Ishiwata, Kiichi

AU - Watanuki, Seiichi

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