Different responses in postprandial plasma ghrelin and GH levels induced by concentrate or timothy hay feeding in wethers

T. Takahashi, Y. Kobayashi, S. Hasegawa, E. Touno, Y. Otani, S. Haga, F. Itoh, Kazuo Katoh, Y. Obara

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)

    Abstract

    Ghrelin and growth hormone (GH) play a key role in regulating energy balance, metabolic hormone secretion and food intake. Ghrelin and GH responses to dietary compositions have not yet been fully clarified, although there may be significant relationships between dietary compositions and ghrelin and GH responses. In the present study, therefore, we assessed whether dietary compositions influence postprandial plasma ghrelin and GH levels in wethers. Four wethers were respectively fed concentrate (C) or timothy hay (R) for 14 days. The levels of total digestive nutrients (TDN) and crude protein (CP) were adjusted to be at the same level. The basal ghrelin in both groups was rapidly and significantly decreased after feeding. Although the decline of ghrelin levels in C was greater and shorter than that in R, no significant difference was observed in the area under the curve (AUC) or in the incremental area. The plasma GH levels were also rapidly and significantly decreased after feeding in both groups and a significant difference was observed between the two groups for AUC of GH. Interestingly, the circadian changes in the plasma ghrelin levels were close to those in the GH levels in C, but this was not the case in R. These data suggest that dietary compositions influence postprandial plasma ghrelin and GH levels, and that these differences may be caused by several factors, including nutrients and ruminal fermentation.

    Original languageEnglish
    Pages (from-to)432-439
    Number of pages8
    JournalDomestic Animal Endocrinology
    Volume34
    Issue number4
    DOIs
    Publication statusPublished - 2008 May 1

    Keywords

    • Concentrate
    • GH
    • Ghrelin
    • Timothy hay
    • Wether

    ASJC Scopus subject areas

    • Food Animals
    • Animal Science and Zoology
    • Endocrinology

    Fingerprint Dive into the research topics of 'Different responses in postprandial plasma ghrelin and GH levels induced by concentrate or timothy hay feeding in wethers'. Together they form a unique fingerprint.

    Cite this