Differences in sleep architecture between left and right temporal lobe epilepsy

Miki Nakamura, Kazutaka Jin, Kazuhiro Kato, Hisashi Itabashi, Masaki Iwasaki, Yosuke Kakisaka, Nobukazu Nakasato

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

To investigate whether seizure lateralization affects sleep macrostructure in patients with left and right temporal lobe epilepsy (TLE), as rapid eye movement (REM) sleep is shorter in patients with right hemispheric cerebral infarction than with left. We retrospectively analyzed data from 16 patients with TLE (6 men and 10 women aged 34.9 ± 11.4 years) who underwent polysomnography as well as long-term video electroencephalography. Ten patients were diagnosed with left TLE and six patients with right TLE. Sleep stages and respiratory events were scored based on the American Academy of Sleep Medicine criteria. Sleep and respiratory parameters were compared between the patient groups. Percentage of REM stage sleep was significantly (p < 0.05) lower in patients with left TLE (median 8.8 %, interquartile range 5.5–13.8 %) than in patients with right TLE (median 17.0 %, interquartile range 14.1–18.3 %). The other parameters showed no significant differences. Shorter REM sleep in patients with left TLE sharply contrasts with the previous report of shorter REM sleep in patients with right cerebral infarction. Laterality of the irritative epileptic focus versus destructive lesion may have different effects on the sleep macrostructures.

Original languageEnglish
Pages (from-to)189-192
Number of pages4
JournalNeurological Sciences
Volume38
Issue number1
DOIs
Publication statusPublished - 2017 Jan 1

Keywords

  • Polysomnography
  • REM sleep
  • Seizure lateralization
  • Sleep architecture
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

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