Diagnostic thresholds for ambulatory blood pressure moving lower: A review based on a meta-analysis-clinical implications

Tine T. Hansen, Masahiro Kikuya, Lutgarde Thijs, Yan Li, José Boggia, Kristina Björklund-Bodegârd, Christian Torp-Pedersen, Jørgen Jeppesen, Hans Ibsen, Jan J. Staessen

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Upper limits of normal ambulatory blood pressure (ABP) have been a matter of debate in recent years. Current diagnostic thresholds for ABP rely mainly on statistical parameters derived from reference populations. Recent findings from the International Database of Ambulatory Blood Pressure in Relation to Cardiovascular Outcome (IDACO) provide outcome-driven thresholds for ABP. Rounded systolic/diastolic thresholds for optimal ABP were found to be 115/75 mm Hg for 24 hours, 120/80 mm Hg for daytime, and 100/65 mm Hg for nighttime. The corresponding rounded thresholds for normal ABP were 125/75 mm Hg, 130/85 mm Hg, and 110/70 mm Hg, respectively, and those for ambulatory hypertension were 130/80 mm Hg, 140/85 mm Hg, and 120/70 mm Hg. However, in clinical practice, any diagnostic threshold for blood pressure needs to be assessed in the context of the patient's overall risk profile. The IDACO database is therefore being updated with additional population cohorts to enable the construction of multifactorial risk score charts, which also include ABP.

Original languageEnglish
Pages (from-to)377-381
Number of pages5
JournalJournal of Clinical Hypertension
Volume10
Issue number5
DOIs
Publication statusPublished - 2008 May

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

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