TY - JOUR
T1 - Diagnostic performance of detecting breast cancer on computed radiographic (CR) mammograms
T2 - Comparison of hard copy film, 3-megapixel liquid-crystal-display (LCD) monitor and 5-megapixel LCD monitor
AU - Yamada, Takayuki
AU - Suzuki, Akihiko
AU - Uchiyama, Nachiko
AU - Ohuchi, Noriaki
AU - Takahashi, Shoki
N1 - Funding Information:
The authors gratefully acknowledge the important contributions of Drs. Furuta Akemi, Furuta Akihiko, Kakukawa Youichirou, Katayama Masami, Tsunoda Hiroko, Takehana Kyo, Kuchiki Megumi, Saitou Mioko, Kawai Ken, and Shimada Naoko. This study was supported by a grant from the Toshio Kurokawa Cancer Research Fund and constitutes one of the studies conducted by the Ministry of Health, Labor, and Welfare.
PY - 2008
Y1 - 2008
N2 - The purpose was to compare observer performance in the detection of breast cancer using hard-copy film, and 3-megapixel (3-MP) and 5-megapixel (5-MP) liquid crystal display (LCD) monitors in a simulated screening setting. We amassed 100 sample sets, including 32 patients with surgically proven breast cancer (masses present, N = 12; microcalcifications, N = 10; other types, N = 10) and 68 normal controls. All the mammograms were obtained using computed radiography (CR; sampling pitch of 50 μm). Twelve mammographers independently assessed CR mammograms presented in random order for hard-copy and soft-copy reading at minimal 4-week intervals. Observers rated the images on seven-point (1 to 7) and continuous (0 to 100) malignancy scales. Receiver-operating-characteristics analysis was performed, and the average area under the curve (AUC) was calculated for each modality. The jackknife method with the Bonferroni correction was applied to multireader/multicase analysis. The average AUC values for the 3-MP LCD, 5-MP LCD, and hard-copy film were 0.954, 0.947, and 0.956 on the seven-point scale and 0.943, 0.923, and 0.944 on the continuous scale, respectively. There were no significant differences among the three modalities on either scale. Soft-copy reading using 3-MP and 5-MP LCDs is comparable to hard-copy reading for detecting breast cancer.
AB - The purpose was to compare observer performance in the detection of breast cancer using hard-copy film, and 3-megapixel (3-MP) and 5-megapixel (5-MP) liquid crystal display (LCD) monitors in a simulated screening setting. We amassed 100 sample sets, including 32 patients with surgically proven breast cancer (masses present, N = 12; microcalcifications, N = 10; other types, N = 10) and 68 normal controls. All the mammograms were obtained using computed radiography (CR; sampling pitch of 50 μm). Twelve mammographers independently assessed CR mammograms presented in random order for hard-copy and soft-copy reading at minimal 4-week intervals. Observers rated the images on seven-point (1 to 7) and continuous (0 to 100) malignancy scales. Receiver-operating-characteristics analysis was performed, and the average area under the curve (AUC) was calculated for each modality. The jackknife method with the Bonferroni correction was applied to multireader/multicase analysis. The average AUC values for the 3-MP LCD, 5-MP LCD, and hard-copy film were 0.954, 0.947, and 0.956 on the seven-point scale and 0.943, 0.923, and 0.944 on the continuous scale, respectively. There were no significant differences among the three modalities on either scale. Soft-copy reading using 3-MP and 5-MP LCDs is comparable to hard-copy reading for detecting breast cancer.
KW - Breast neoplasm
KW - Data display
KW - Digital radiography
KW - Liquid crystals
KW - ROC curve
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U2 - 10.1007/s00330-008-1016-8
DO - 10.1007/s00330-008-1016-8
M3 - Article
C2 - 18491108
AN - SCOPUS:54049098447
VL - 18
SP - 2363
EP - 2369
JO - European Radiology
JF - European Radiology
SN - 0938-7994
IS - 11
ER -
