Diagnostic performance of detecting breast cancer on computed radiographic (CR) mammograms: Comparison of hard copy film, 3-megapixel liquid-crystal-display (LCD) monitor and 5-megapixel LCD monitor

Takayuki Yamada, Akihiko Suzuki, Nachiko Uchiyama, Noriaki Ohuchi, Syouki Takahashi

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

The purpose was to compare observer performance in the detection of breast cancer using hard-copy film, and 3-megapixel (3-MP) and 5-megapixel (5-MP) liquid crystal display (LCD) monitors in a simulated screening setting. We amassed 100 sample sets, including 32 patients with surgically proven breast cancer (masses present, N = 12; microcalcifications, N = 10; other types, N = 10) and 68 normal controls. All the mammograms were obtained using computed radiography (CR; sampling pitch of 50 μm). Twelve mammographers independently assessed CR mammograms presented in random order for hard-copy and soft-copy reading at minimal 4-week intervals. Observers rated the images on seven-point (1 to 7) and continuous (0 to 100) malignancy scales. Receiver-operating-characteristics analysis was performed, and the average area under the curve (AUC) was calculated for each modality. The jackknife method with the Bonferroni correction was applied to multireader/multicase analysis. The average AUC values for the 3-MP LCD, 5-MP LCD, and hard-copy film were 0.954, 0.947, and 0.956 on the seven-point scale and 0.943, 0.923, and 0.944 on the continuous scale, respectively. There were no significant differences among the three modalities on either scale. Soft-copy reading using 3-MP and 5-MP LCDs is comparable to hard-copy reading for detecting breast cancer.

Original languageEnglish
Pages (from-to)2363-2369
Number of pages7
JournalEuropean Radiology
Volume18
Issue number11
DOIs
Publication statusPublished - 2008

Keywords

  • Breast neoplasm
  • Data display
  • Digital radiography
  • Liquid crystals
  • ROC curve

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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