Abstract
Neuromyelitis optica (NMO) is an autoimmune central nervous system disease associated with anti-aquaporin 4 (AQP4) antibody. Although the current diagnostic criteria requires both optic neuritis and myelitis, many of the patients with anti-AQP4 antibody do not fulfil the criteria, so that they have a chance to be misdiagnosed as having multiple sclerosis (MS). To avoid the misdiagnosis, a sensitive method to detect anti-AQP4 antibody is required although widely used kits has lower sensitivity. Although MS is one of the most important differential diagnosis of NMO, diseases associated with anti-myelin oligodendrocyte glycoprotein antibody may mimic NMO clinical features and should be considered as differential diagnosis.
Original language | English |
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Pages (from-to) | 1964-1969 |
Number of pages | 6 |
Journal | Nihon rinsho. Japanese journal of clinical medicine |
Volume | 72 |
Issue number | 11 |
Publication status | Published - 2014 Nov 1 |
Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)