Diagnosis of intracranial malignant lymphoma by 67Ga and 201Tl SPECT

O. Nakamura; K. Okamoto; M. Kaneko; H. Nakamura; N. Shitara; K. Suzuki; S. Kosuda

Diagnosis of intracranial malignant lymphoma by ⁶⁷Ga and ²⁰¹Tl SPECT

O. Nakamura, K. Okamoto, M. Kaneko, H. Nakamura, N. Shitara, K. Suzuki, S. Kosuda

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Six patients with malignant lymphoma of the brain underwent ⁶⁷Ga and ²⁰¹Tl brain SPECT. For the quantitative analysis, count ratios of a lesion to the normal brain (L/N) were calculated. In ²⁰¹Tl SPECT studies, an L/N ratios ranged from 2.3 to 3.2, with a mean of 2.9 ± 0.4. In ⁶⁷Ga SPECT studies, an L/N ratios ranged from 4.4 to 6.6 with a mean of 5.7 ± 0.8. ⁶⁷Ga SPECT showed much more intense tracer uptake than ²⁰¹Tl SPECT and the degree of ⁶⁷Ga accumulation seems to be in proportion to the viability of malignant lymphoma. We came to the conclusion that quantitative ⁶⁷Ga SPECT appears to be useful in detecting and managing malignant lymphoma in the brain.

Original language	English
Pages (from-to)	215-219
Number of pages	5
Journal	Japanese Journal of Clinical Radiology
Volume	40
Issue number	2
Publication status	Published - 1995

Keywords

brain tumors
gallium SPECT
malignant lymphoma
thallium SPECT

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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title = "Diagnosis of intracranial malignant lymphoma by 67Ga and 201Tl SPECT",

abstract = "Six patients with malignant lymphoma of the brain underwent 67Ga and 201Tl brain SPECT. For the quantitative analysis, count ratios of a lesion to the normal brain (L/N) were calculated. In 201Tl SPECT studies, an L/N ratios ranged from 2.3 to 3.2, with a mean of 2.9 ± 0.4. In 67Ga SPECT studies, an L/N ratios ranged from 4.4 to 6.6 with a mean of 5.7 ± 0.8. 67Ga SPECT showed much more intense tracer uptake than 201Tl SPECT and the degree of 67Ga accumulation seems to be in proportion to the viability of malignant lymphoma. We came to the conclusion that quantitative 67Ga SPECT appears to be useful in detecting and managing malignant lymphoma in the brain.",

keywords = "brain tumors, gallium SPECT, malignant lymphoma, thallium SPECT",

author = "O. Nakamura and K. Okamoto and M. Kaneko and H. Nakamura and N. Shitara and K. Suzuki and S. Kosuda",

year = "1995",

language = "English",

volume = "40",

pages = "215--219",

journal = "Japanese Journal of Clinical Radiology",

issn = "0009-9252",

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TY - JOUR

T1 - Diagnosis of intracranial malignant lymphoma by 67Ga and 201Tl SPECT

AU - Nakamura, O.

AU - Okamoto, K.

AU - Kaneko, M.

AU - Nakamura, H.

AU - Shitara, N.

AU - Suzuki, K.

AU - Kosuda, S.

PY - 1995

Y1 - 1995

N2 - Six patients with malignant lymphoma of the brain underwent 67Ga and 201Tl brain SPECT. For the quantitative analysis, count ratios of a lesion to the normal brain (L/N) were calculated. In 201Tl SPECT studies, an L/N ratios ranged from 2.3 to 3.2, with a mean of 2.9 ± 0.4. In 67Ga SPECT studies, an L/N ratios ranged from 4.4 to 6.6 with a mean of 5.7 ± 0.8. 67Ga SPECT showed much more intense tracer uptake than 201Tl SPECT and the degree of 67Ga accumulation seems to be in proportion to the viability of malignant lymphoma. We came to the conclusion that quantitative 67Ga SPECT appears to be useful in detecting and managing malignant lymphoma in the brain.

AB - Six patients with malignant lymphoma of the brain underwent 67Ga and 201Tl brain SPECT. For the quantitative analysis, count ratios of a lesion to the normal brain (L/N) were calculated. In 201Tl SPECT studies, an L/N ratios ranged from 2.3 to 3.2, with a mean of 2.9 ± 0.4. In 67Ga SPECT studies, an L/N ratios ranged from 4.4 to 6.6 with a mean of 5.7 ± 0.8. 67Ga SPECT showed much more intense tracer uptake than 201Tl SPECT and the degree of 67Ga accumulation seems to be in proportion to the viability of malignant lymphoma. We came to the conclusion that quantitative 67Ga SPECT appears to be useful in detecting and managing malignant lymphoma in the brain.

KW - brain tumors

KW - gallium SPECT

KW - malignant lymphoma

KW - thallium SPECT

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