Development of total artificial heart with economical and durability advantages

T. Yambe, A. Fukutome, S. Kobayashi, S. Nanka, M. Yoshizawa, K. Tabayashi, H. Takeda, S. Nitta

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

To develop a total artificial heart (TAH) pump system, we created a design paying particular attention to durability and cost. We adopted a pneumatically driven sac type artificial heart, where the configuration of the sac was decided according to the methodology of flow visualization. Its configuration is almost round to achieve as little stagnation as possible and a low turbulent flow. The main body of the sac was made using polyvinyl chloride (PVC) paste. The paste was poured into an external mold, and heated in a hot air drying oven. Coating was performed using polyurethane. The basic performance of this pump system was tested using a model circulation circuit, and a fitting study through acute animal experiment, using a healthy adult goat, was carried out. As for the TAH produced experimentally, a pump output exceeding 5.0 l/min in the model circulation circuit was provided. Implantation in the internal pleural cavity of a healthy adult goat, 55 kg in weight, proved possible and quite easy in comparison. It is thought that a more refined design in the connector part is desirable. Furthermore, a chronic experiment with the TAH will be carried out, and examination will need to be repeated in the future.

Original languageEnglish
Pages (from-to)279-284
Number of pages6
JournalInternational Journal of Artificial Organs
Volume21
Issue number5
DOIs
Publication statusPublished - 1998 May

Keywords

  • Economy
  • Flow visualization
  • Pneumatically driven
  • Silicone ball valve
  • Total artificial heart

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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