Development of pulmonary alveolar proteinosis following exposure to dust after the great east japan earthquake

Shu Hisata, Hiroshi Moriyama, Ryushi Tazawa, Shinya Ohkouchi, Masakazu Ichinose, Masahito Ebina

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

We report a unique case of pulmonary alveolar proteinosis that developed 3 weeks after the Great East Japan Earthquake and the subsequent tsunami. The patient had inhaled dust repeatedly while visiting her devastated neighborhood without wearing a protective mask. Five weeks after the earthquake, lung samples taken from the patient showed foreign particle deposition; however, her serum was negative for GM-CSF autoantibody. The patient's clinical symptoms resolved following whole lung lavage. We conclude that inhalation of fine dust particles after natural disasters may cause the onset of pulmonary alveolar proteinosis.

Original languageEnglish
Pages (from-to)212-216
Number of pages5
JournalRespiratory Investigation
Volume51
Issue number4
DOIs
Publication statusPublished - 2013 Dec

Keywords

  • Earthquake
  • GM-CSF autoantibody
  • Pulmonary alveolar proteinosis
  • Whole lung lavage

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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