Development of precolumn complexation - Reversed-phase partition liquid chromatography for the ultratrace detection of metal ions

Hitoshi Hoshino

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The analytical practicability of precolumn complexation - reversed-phase partition liquid chromatography in ultratrace metal detection has been exemplified by successful applications to aluminium determination in high-purity alkali hydroxide pellets and ground water samples. High sensitivity with extraordinary matrix toughness of the HPLC methods has been also emphasized with air-borne particulate analyses for beryllium, vanadium and nickel. The complexation reagents employed were tridentate ligands with N, O donor functions, such as 2,2′-dihydroxyazobenzene, H-resorcinol and some hydrazones. Additionally, an on-line preconcentration system connected to the HPLC has been shown for the detection of cobalt in the ppt range as the 4-(2-pyridylazo)resorcinolato complex. The underlying chemistry at work in the precolumn complexation - HPLC processes has been described in terms of the ultrahigh sensitivity and the specificity to certain metal ions. The kinetic aspect of the complex dissociation reactions potentially taking place during elution is crucial for designing the precolumn complexation HPLC to give unique kinetically-controlled selectivity to metal complexes.

Original languageEnglish
Pages (from-to)597-604
Number of pages8
JournalBUNSEKI KAGAKU
Volume51
Issue number8
DOIs
Publication statusPublished - 2002 Aug

Keywords

  • HPLC
  • Metal complex
  • Precolumn complexation
  • Trace metal analysis

ASJC Scopus subject areas

  • Analytical Chemistry

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