Development of Organic Plate Particle Powder by Melt Crystallization in Supercritical Carbon Dioxide

Takuya Imaki, Koji Mine, Hedeaki Kubo, Yoshiyuki Sato, Hiroshi Inomata

Research output: Contribution to journalArticlepeer-review

Abstract

Sphingolipid E (SLE) is a synthesized sphingolipid on the model of ceramide. SLE plate particles could be produced via crystallization by cooling the SLE melt solution in the presence of supercritical carbon dioxide and were obtained as fine powder after depressurization. It was estimated that the particle aggregation was reduced by depressurization together with cooling. The obtained SLE plate particle powder contains no residual solvent and is pleasant to the touch, indicating its potential for use in cosmetics with moisturizing effect.

Original languageEnglish
Pages (from-to)580-586
Number of pages7
Journalkagaku kogaku ronbunshu
Volume34
Issue number6
DOIs
Publication statusPublished - 2008 Dec 1

Keywords

  • Ceramide
  • Melt Crystallization
  • Organic Plate Particles Powder
  • Solubility
  • Supercritical Carbon Dioxide

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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