Development of molecular imaging probes in oncology

Ren Iwata

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    Molecular imaging probes used for positron emission tomography(PET)in oncology are reviewed. Although [18F] FDG is presently the most useful probe for imaging tumors, there is a need for complementary probes of FDG with some limitations on detection in the brain or inflammatory region. The review is mostly focused on 18F-labeled probes designed for amino acid transport and protein synthesis, DNA synthesis, membrane lipid, and hypoxia such as FET, FLT, FMAU, fluorocholine, and FMISO, together with our original probes of FMT and FRP-170.

    Original languageEnglish
    Pages (from-to)1286-1290
    Number of pages5
    JournalGan to kagaku ryoho. Cancer & chemotherapy
    Volume35
    Issue number8
    Publication statusPublished - 2008 Aug

    ASJC Scopus subject areas

    • Oncology
    • Cancer Research

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