Development of magnet configurations for magnetic immunostaining

Miki Kaneko, Shinichi Chikaki, Sachiko Matsuda, Akihiro Kuwahata, Masayuki Namita, Itsuro Saito, Satoshi Sakamoto, Moriaki Kusakabe, Masaki Sekino

Research output: Contribution to journalArticlepeer-review

Abstract

Magnetic immunostaining using a magnet and antibody-labeled fluorescent ferrite (FF) beads is established as a rapid immunostaining. In this study, we proposed the novel configuration of magnets with the large magnetic field gradient and the strong magnetic force for magnetic immunostaining. To confirm the usefulness of the proposed magnet configuration, we performed numerical analysis of the magnetic characteristics of the proposed magnets, and the magnetic immunostaining with FF beads. It was revealed that the proposed magnets generated the strong magnetic force and promoted the immunoreaction rapidly.

Original languageEnglish
Article number056732
JournalAIP Advances
Volume8
Issue number5
DOIs
Publication statusPublished - 2018 May 1
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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