Abstract
A new method for Madelung-type indole synthesis was investigated, and it was found that the amidation of 2-iodophenylacetonitrile with various alkanamides proceeds smoothly in the presence of CuI and a diamine ligand. The subsequent cyclization of the C-N coupling products takes place under the coupling reaction conditions.
Original language | English |
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Pages (from-to) | 900-909 |
Number of pages | 10 |
Journal | Heterocycles |
Volume | 92 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2016 |
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry