Development of integrated electronics unit for drive and control of undulation pump-left ventricular assist device

Eiji Okamoto; Tsutomu Makino; Yusuke Inoue; Shuji Tanaka; Takahiko Yasuda; Masatoshi Nakamura; Itsuro Saito; Yusuke Abe; Tsuneo Chinzei; Takashi Isoyama; Shuichi Mochiizuki; Kou Imachi; Yoshinori Mitamura

doi:10.1111/j.1525-1594.2006.00233.x

Development of integrated electronics unit for drive and control of undulation pump-left ventricular assist device

Eiji Okamoto, Tsutomu Makino, Yusuke Inoue, Shuji Tanaka, Takahiko Yasuda, Masatoshi Nakamura, Itsuro Saito, Yusuke Abe, Tsuneo Chinzei, Takashi Isoyama, Shuichi Mochiizuki, Kou Imachi, Yoshinori Mitamura

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic subunits were encapsulated in a case (110 × ∼80 × ∼30 mm) made of epoxy resin. The IEU was evaluated in two animal experiments using goats implanted with the UP-LVAD. The lithium ion batteries in the IEU provided 30-min energy supply daily to the UP-LVAD. The transcutaneous information transmission system transmitted data bidirectionally between the IEU and the personal computer at the data transmission ratio of 56 kbps without any transmission error. We could obtain survival days of 27 and 28 days supporting cardiac function with the UP-LVAD system. The temperature inside the IEU case was maintained under 45°C, and there was evidence of a burn on the surrounding tissue in autopsies in each experiment. Based on the results, the IEU is promising to be suitable for drive and control of an implantable UP-LVAD.

Original language	English
Pages (from-to)	403-405
Number of pages	3
Journal	Artificial Organs
Volume	30
Issue number	5
DOIs	https://doi.org/10.1111/j.1525-1594.2006.00233.x
Publication status	Published - 2006 May
Externally published	Yes

Keywords

Artificial heart
Information
Lithium ion battery
Undulation pump
Ventricular assist device

ASJC Scopus subject areas

Bioengineering
Medicine (miscellaneous)
Biomaterials
Biomedical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/j.1525-1594.2006.00233.x

Cite this

Okamoto, E., Makino, T., Inoue, Y., Tanaka, S., Yasuda, T., Nakamura, M., Saito, I., Abe, Y., Chinzei, T., Isoyama, T., Mochiizuki, S., Imachi, K., & Mitamura, Y. (2006). Development of integrated electronics unit for drive and control of undulation pump-left ventricular assist device. Artificial Organs, 30(5), 403-405. https://doi.org/10.1111/j.1525-1594.2006.00233.x

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abstract = "In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic subunits were encapsulated in a case (110 × ∼80 × ∼30 mm) made of epoxy resin. The IEU was evaluated in two animal experiments using goats implanted with the UP-LVAD. The lithium ion batteries in the IEU provided 30-min energy supply daily to the UP-LVAD. The transcutaneous information transmission system transmitted data bidirectionally between the IEU and the personal computer at the data transmission ratio of 56 kbps without any transmission error. We could obtain survival days of 27 and 28 days supporting cardiac function with the UP-LVAD system. The temperature inside the IEU case was maintained under 45°C, and there was evidence of a burn on the surrounding tissue in autopsies in each experiment. Based on the results, the IEU is promising to be suitable for drive and control of an implantable UP-LVAD.",

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author = "Eiji Okamoto and Tsutomu Makino and Yusuke Inoue and Shuji Tanaka and Takahiko Yasuda and Masatoshi Nakamura and Itsuro Saito and Yusuke Abe and Tsuneo Chinzei and Takashi Isoyama and Shuichi Mochiizuki and Kou Imachi and Yoshinori Mitamura",

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doi = "10.1111/j.1525-1594.2006.00233.x",

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AU - Okamoto, Eiji

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AU - Tanaka, Shuji

AU - Yasuda, Takahiko

AU - Nakamura, Masatoshi

AU - Saito, Itsuro

AU - Abe, Yusuke

AU - Chinzei, Tsuneo

AU - Isoyama, Takashi

AU - Mochiizuki, Shuichi

AU - Imachi, Kou

AU - Mitamura, Yoshinori

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AB - In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic subunits were encapsulated in a case (110 × ∼80 × ∼30 mm) made of epoxy resin. The IEU was evaluated in two animal experiments using goats implanted with the UP-LVAD. The lithium ion batteries in the IEU provided 30-min energy supply daily to the UP-LVAD. The transcutaneous information transmission system transmitted data bidirectionally between the IEU and the personal computer at the data transmission ratio of 56 kbps without any transmission error. We could obtain survival days of 27 and 28 days supporting cardiac function with the UP-LVAD system. The temperature inside the IEU case was maintained under 45°C, and there was evidence of a burn on the surrounding tissue in autopsies in each experiment. Based on the results, the IEU is promising to be suitable for drive and control of an implantable UP-LVAD.

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KW - Undulation pump

KW - Ventricular assist device

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Development of integrated electronics unit for drive and control of undulation pump-left ventricular assist device

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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