A novel ?-type titanium alloy with a changeable Young's modulus, that is, with a low Young's modulus to prevent the stress-shielding effect for patients and a high Young's modulus to suppress springback for surgeons, should be developed in order to satisfy the conflicting requirements of both the patients and surgeons in spinal fixation operations. In this study, the oxygen content in ternary Ti-11Cr-O alloys was optimized in order to achieve a large changeable Young's modulus with good mechanical properties for spinal fixation applications. The increase in Young's moduli of all the examined alloys by cold rolling is attributed to the deformation-induced ?-phase transformation which is suppressed by oxygen. Among the examined alloys, the Ti-11Cr-0.2O alloy exhibits the largest changeable Young's modulus and a high tensile strength with an acceptable plasticity under both solution-treated (ST) and cold-rolled (CR) conditions. Therefore, the Ti-11Cr-0.2O alloy, which shows a good balance among a changeable Young's modulus, high tensile strength and good plasticity, is considered a potential candidate for spinal fixation applications.