Development of biomaterials using marine-derived salmon collagen

Nobuhiro Nagai, Shunji Yunoki, Kazuo Mori, Toshiyuki Kanayama, Yasuharu Satoh, Kenji Tajima, Masanobu Munekata

Research output: Contribution to conferencePaperpeer-review


We successfully prepared the thermostable scaffolds, such as a porous sponge, fibrillargel, and elastic gel, from salmon atelocollagen (SC) using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide cross-linking. We applied these cross-linked SC scaffolds to the in vitro cell culture of human periodontal ligament cells. As a result, the attachment, growth, and alkaline phosphatase activities of the cells cultured on the SC scaffolds were the same or more than those on the porcine atelocollagen scaffolds. The SC scaffolds could serve as well as the traditional collagen as a scaffold for an in vitro cell culture and tissue engineering.

Original languageEnglish
Number of pages1
Publication statusPublished - 2006 Dec 1
Externally publishedYes
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22


Other55th Society of Polymer Science Japan Symposium on Macromolecules


  • Biomaterial
  • Marine-derived collagen
  • Salmon
  • Tissue engineering

ASJC Scopus subject areas

  • Engineering(all)


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