Development of biomaterials using marine-derived salmon collagen

Nobuhiro Nagai; Shunji Yunoki; Kazuo Mori; Toshiyuki Kanayama; Yasuharu Satoh; Kenji Tajima; Masanobu Munekata

Development of biomaterials using marine-derived salmon collagen

Nobuhiro Nagai, Shunji Yunoki, Kazuo Mori, Toshiyuki Kanayama, Yasuharu Satoh, Kenji Tajima, Masanobu Munekata

Research output: Contribution to conference › Paper › peer-review

Abstract

We successfully prepared the thermostable scaffolds, such as a porous sponge, fibrillargel, and elastic gel, from salmon atelocollagen (SC) using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide cross-linking. We applied these cross-linked SC scaffolds to the in vitro cell culture of human periodontal ligament cells. As a result, the attachment, growth, and alkaline phosphatase activities of the cells cultured on the SC scaffolds were the same or more than those on the porcine atelocollagen scaffolds. The SC scaffolds could serve as well as the traditional collagen as a scaffold for an in vitro cell culture and tissue engineering.

Original language	English
Number of pages	1
Publication status	Published - 2006 Dec 1
Externally published	Yes
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: 2006 Sep 20 → 2006 Sep 22

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
Country	Japan
City	Toyama
Period	06/9/20 → 06/9/22

Keywords

Biomaterial
Marine-derived collagen
Salmon
Tissue engineering

ASJC Scopus subject areas

Engineering(all)

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Cite this

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title = "Development of biomaterials using marine-derived salmon collagen",

abstract = "We successfully prepared the thermostable scaffolds, such as a porous sponge, fibrillargel, and elastic gel, from salmon atelocollagen (SC) using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide cross-linking. We applied these cross-linked SC scaffolds to the in vitro cell culture of human periodontal ligament cells. As a result, the attachment, growth, and alkaline phosphatase activities of the cells cultured on the SC scaffolds were the same or more than those on the porcine atelocollagen scaffolds. The SC scaffolds could serve as well as the traditional collagen as a scaffold for an in vitro cell culture and tissue engineering.",

keywords = "Biomaterial, Marine-derived collagen, Salmon, Tissue engineering",

author = "Nobuhiro Nagai and Shunji Yunoki and Kazuo Mori and Toshiyuki Kanayama and Yasuharu Satoh and Kenji Tajima and Masanobu Munekata",

year = "2006",

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language = "English",

note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

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TY - CONF

T1 - Development of biomaterials using marine-derived salmon collagen

AU - Nagai, Nobuhiro

AU - Yunoki, Shunji

AU - Mori, Kazuo

AU - Kanayama, Toshiyuki

AU - Satoh, Yasuharu

AU - Tajima, Kenji

AU - Munekata, Masanobu

PY - 2006/12/1

Y1 - 2006/12/1

N2 - We successfully prepared the thermostable scaffolds, such as a porous sponge, fibrillargel, and elastic gel, from salmon atelocollagen (SC) using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide cross-linking. We applied these cross-linked SC scaffolds to the in vitro cell culture of human periodontal ligament cells. As a result, the attachment, growth, and alkaline phosphatase activities of the cells cultured on the SC scaffolds were the same or more than those on the porcine atelocollagen scaffolds. The SC scaffolds could serve as well as the traditional collagen as a scaffold for an in vitro cell culture and tissue engineering.

AB - We successfully prepared the thermostable scaffolds, such as a porous sponge, fibrillargel, and elastic gel, from salmon atelocollagen (SC) using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide cross-linking. We applied these cross-linked SC scaffolds to the in vitro cell culture of human periodontal ligament cells. As a result, the attachment, growth, and alkaline phosphatase activities of the cells cultured on the SC scaffolds were the same or more than those on the porcine atelocollagen scaffolds. The SC scaffolds could serve as well as the traditional collagen as a scaffold for an in vitro cell culture and tissue engineering.

KW - Biomaterial

KW - Marine-derived collagen

KW - Salmon

KW - Tissue engineering

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M3 - Paper

AN - SCOPUS:33846133770

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -