Development of autonomic regulation model for cardiovascular system simulations

Tomonobu Goto, Hiroto Sakamoto, Atsushi Utsunomiya, Kenta Shishikura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In order to evaluate health risks under sever thermal environments, we are developing a new human model that can predict BP and BFR, as well as body temperature. In this study, we developed one of the sub-models for our human model, i.e. autonomic regulation model, which predicts human responses on vasomotor and cardiac activities for thermoregulation and baroreflex. We also conducted some simulations by using the autonomic regulation model combined with our previously developed model of cardiovascular system. The results showed that the simulations reproduced reasonably the actual BP and BFR under four different thermal and postural conditions, i.e. 18°C, 28°C, 40°C-supine and 28°C-standing. Only in the 18°C-supine case, there was a substantial problem on the BP simulation, however, it will be solved by the incorporation of more precise vasomotor activity.

Original languageEnglish
Title of host publication16th Conference of the International Society of Indoor Air Quality and Climate
Subtitle of host publicationCreative and Smart Solutions for Better Built Environments, Indoor Air 2020
PublisherInternational Society of Indoor Air Quality and Climate
ISBN (Electronic)9781713823605
Publication statusPublished - 2020
Event16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020 - Virtual, Online
Duration: 2020 Nov 1 → …

Publication series

Name16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020

Conference

Conference16th Conference of the International Society of Indoor Air Quality and Climate: Creative and Smart Solutions for Better Built Environments, Indoor Air 2020
CityVirtual, Online
Period20/11/1 → …

Keywords

  • Blood flow rate
  • Blood pressure
  • Health risk
  • Human model
  • Thermal environment

ASJC Scopus subject areas

  • Building and Construction
  • Computer Science Applications
  • Health, Toxicology and Mutagenesis
  • Pollution

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