Development of an inhalation anesthetic device for mouse pups equipped with brain stereotaxic function

Shotaro Yoshida, Y. Morimoto, T. Tonooka, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Brain stereotaxic surgery is a useful tool in system neuroscience. However, the surgery in mouse pups has difficulties caused by anesthetic control and brain stereotaxis. Here, we develop an inhalation anesthetic device equipped with brain stereotaxic function specialized for mouse pups. We successfully anesthetized a pup and performed brain microinjection at once using this single device. The pup recovered quickly when it was removed from the device. Since the channel fabrication process is compatible to integrate with various fluidic components, our approach will provide a handy and functional instrument for stereotaxic surgery in the developing brain.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages1054-1055
Number of pages2
ISBN (Electronic)9780979806476
Publication statusPublished - 2014 Jan 1
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period14/10/2614/10/30

Keywords

  • 3D printer
  • Brain stereotaxis
  • Inhalation anesthesia
  • Microinjection
  • Mouse pup

ASJC Scopus subject areas

  • Control and Systems Engineering

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