TY - JOUR
T1 - Development of a thermodynamic control system for the Fontan circulation pulsation device using shape memory alloy fibers
AU - Yamada, Akihiro
AU - Shiraishi, Yasuyuki
AU - Miura, Hidekazu
AU - Hashem, Hashem Mohamed Omran
AU - Tsuboko, Yusuke
AU - Yamagishi, Masaaki
AU - Yambe, Tomoyuki
N1 - Funding Information:
This work was supported by JSPS KAKENHI Grant Number 25282126, 26560199, and JSPS Fellows Grant Number 26·6949.
Publisher Copyright:
© 2015, The Japanese Society for Artificial Organs.
PY - 2015/9/4
Y1 - 2015/9/4
N2 - The Fontan procedure is one of the common surgical treatments for circulatory reconstruction in pediatric patients with congenital heart disease. In Fontan circulation, low pulsatility may induce localized lung ischemia and may impair the development of pulmonary peripheral endothelial cells. To promote pulmonary circulation in Fontan circulation, we have been developing a pediatric pulmonary circulatory pulsation device using shape memory alloy fibers attached from the outside of total cavopulmonary connection. In this study, we developed a new thermal control system for the device and examined its functions. We mounted on the device 16 fibers connected in parallel around an ePTFE graft circumferentially. To provide optimized contraction, we designed the new thermal control system. The system consisted of a thermistor, a pressure sensor, and a regulator that was controlled by the adaptive thermodynamic transfer functions. We monitored the parameters and calculated heat transfer function as well as pressure distribution on the graft surface. Then we examined and compared the dynamic contractile pressure and changes in surface temperature. As a result, by the application of the control based on the new feedback system analysis, the circumferential contractile pressure increased by 35 %. The adaptive thermodynamic regulation was useful for the selection of alternative thresholds of the surface temperature of the graft. The system could achieve effective contraction for the pulsatile flow generation by the device.
AB - The Fontan procedure is one of the common surgical treatments for circulatory reconstruction in pediatric patients with congenital heart disease. In Fontan circulation, low pulsatility may induce localized lung ischemia and may impair the development of pulmonary peripheral endothelial cells. To promote pulmonary circulation in Fontan circulation, we have been developing a pediatric pulmonary circulatory pulsation device using shape memory alloy fibers attached from the outside of total cavopulmonary connection. In this study, we developed a new thermal control system for the device and examined its functions. We mounted on the device 16 fibers connected in parallel around an ePTFE graft circumferentially. To provide optimized contraction, we designed the new thermal control system. The system consisted of a thermistor, a pressure sensor, and a regulator that was controlled by the adaptive thermodynamic transfer functions. We monitored the parameters and calculated heat transfer function as well as pressure distribution on the graft surface. Then we examined and compared the dynamic contractile pressure and changes in surface temperature. As a result, by the application of the control based on the new feedback system analysis, the circumferential contractile pressure increased by 35 %. The adaptive thermodynamic regulation was useful for the selection of alternative thresholds of the surface temperature of the graft. The system could achieve effective contraction for the pulsatile flow generation by the device.
KW - Congenital heart disease
KW - Fontan circulation
KW - Shape memory alloy fiber
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U2 - 10.1007/s10047-015-0827-z
DO - 10.1007/s10047-015-0827-z
M3 - Article
C2 - 25894077
AN - SCOPUS:84940719543
VL - 18
SP - 199
EP - 205
JO - Journal of Artificial Organs
JF - Journal of Artificial Organs
SN - 1434-7229
IS - 3
ER -