Development of a practical image-based scatter correction method for brain perfusion SPECT: Comparison with the TEW method

Miho Shidahara, Hiroshi Watabe, Min Kim Kyeong, Takashi Kato, Shoji Kawatsu, Rikio Kato, Kumiko Yoshimura, Hidehiro Iida, Kengo Ito

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: An image-based scatter correction (IBSC) method was developed to convert scatter-uncorrected into scatter-corrected SPECT images. The purpose of this study was to validate this method by means of phantom simulations and human studies with 99mTc-labeled tracers, based on comparison with the conventional triple energy window (TEW) method. Methods: The IBSC method corrects scatter on the reconstructed image IACμb with Chang's attenuation correction factor. The scatter component image is estimated by convolving IACμb with a scatter function followed by multiplication with an image-based scatter fraction function. The IBSC method was evaluated with Monte Carlo simulations and 99mTc-ethyl cysteinate dimer SPECT human brain perfusion studies obtained from five volunteers. The image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were compared. Results: Using data obtained from the simulations, the image counts and contrast of the scatter-corrected images obtained by the IBSC and TEW methods were found to be nearly identical for both gray and white matter. In human brain images, no significant differences in image contrast were observed between the IBSC and TEW methods. Conclusion: The IBSC method is a simple scatter correction technique feasible for use in clinical routine.

Original languageEnglish
Pages (from-to)1193-1198
Number of pages6
JournalEuropean journal of nuclear medicine and molecular imaging
Volume32
Issue number10
DOIs
Publication statusPublished - 2005 Oct 1
Externally publishedYes

Keywords

  • Attenuation correction
  • Cerebral perfusion
  • Image conversion
  • Scatter correction
  • Single-photon emission tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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