Abstract
This paper describes the development of a Polyvinyl alcohol hydrogel (PVA-H) model for calibration and measurement of temperature using image contrast on MRI using DMSO/H2O as a solvent to alter the freezing and melting points of PVA-H. Tissues exposed to temperature changes above 41°C or below 0°C exhibit increasingly extensive and irreversible damage, depending on the exposure duration. MR images can provide a map of temperature if there is sufficient tissue signal. To evaluate treatment principles using temperature changes (hyperthermia, cryotherapy), a model simulating tissue may be useful to provide a reproducible test environment. PVA-H is water soluble and can be seen on MRI. It can be used to construct complicated shapes such as vascular structure, soft tissues, and so on. Therefore, PVA-H can be useful to measure temperatures and assume the distribution of temperature under treatment. In this paper, we applied PVA-H as a temperature detector and calibrated temperature from image contrast. The results exhibit good capability as a temperature detector not only of high temperature (around 41°C), but also of low temperature (as low as -23°C).
Original language | English |
---|---|
Pages (from-to) | 221-228 |
Number of pages | 8 |
Journal | Technology and Health Care |
Volume | 13 |
Issue number | 4 |
Publication status | Published - 2005 Aug 23 |
Externally published | Yes |
ASJC Scopus subject areas
- Biophysics
- Bioengineering
- Biomaterials
- Information Systems
- Biomedical Engineering
- Health Informatics