Development of a novel scale to assess the quality of life in type 1 diabetic patients for beta cell replacement therapy

Nobuyo Hatanaka, Morihito Takita, Takuhiro Yamaguchi, Masahiro Kami, Shinichi Matsumoto

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The main purpose of beta cell replacement therapy for type 1 diabetic patients is to improve their health-related quality of life (HR-QoL). Previous HR-QoL surveys for beta cell replacement therapy on the point of familial support and public understanding have not been studied adequately. We hypothesize that familial support and public understanding have a significant impact on HR-QoL of type 1 diabetic patients, and low HR-QoL assessed with a new scale is associated with seeking a new therapy. The initial questionnaire with 26 items was created after content validation based on 778 inquiries from patients or associates. One hundred five type 1 diabetic patients answered the questionnaire as well as separate questions about their opinions on beta cell replacement therapy. Finally, the new scale, named the Japanese Insulin-Dependent Diabetic Patient QoL (JAPID-QoL) scale, consisted of 19 items with the following three subscales: diabetes status, familial support and social acceptance. Cronbach's α for overall scale was 0. 878, and those for three subscales were over 0. 70. All items were satisfied with convergent validity. Lower scores on the JAPID-QoL scale were associated with higher interest in and acceptance of beta cell replacement therapy (Spearman's coefficients; r = -0. 25, p < 0. 001 and r = -0. 33, p < 0. 001, respectively) and also correlated with the necessity of psychosomatic care (r = -0. 49, p < 0. 001). Our newly proposed JAPID-QoL scale showed enough reliability and validity to assess HR-QoL of type 1 diabetic patients. The patients who had a low HR-QoL on the JAPID-QoL scale desired to receive beta cell replacement therapy and psychosomatic care.

Original languageEnglish
Pages (from-to)55-64
Number of pages10
JournalDiabetology International
Volume2
Issue number2
DOIs
Publication statusPublished - 2011 Jun

Keywords

  • Familial support
  • Quality of life
  • Social acceptance
  • Transplantation therapy
  • Type 1 diabetes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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