Development of a novel hypoxia maker; [ 18F]FRP-170, and its initial clinical application for tumor imaging

Yoshihiro Takai, E. Nakata, Tomohiro Kaneta, T. Hamatsuka, S. Yamada, Ren Iwata, Y. Funaki, Yoichi Ishikawa, N. Tsujitani

Research output: Contribution to journalArticlepeer-review

Abstract

In clinical study, tumor/muscle ratios from 12 sites of 8 patients evaluated by PET were 0.8-2.14, and average ratio except for radiosensitive malignant lymphoma (1.07) and small cell lung cancer (1.0) was 1.58. Because of low lipophilicity of the tracer, the background activities decreased rapidly. We conclude from these data that [ 18F]FRP-170 is a promising new hypoxia marker in cancer patients.

Original languageEnglish
Pages (from-to)837-843
Number of pages7
JournalJapanese Journal of Clinical Radiology
Volume51
Issue number7
Publication statusPublished - 2006 Aug 15

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Development of a novel hypoxia maker; [ <sup>18</sup>F]FRP-170, and its initial clinical application for tumor imaging'. Together they form a unique fingerprint.

Cite this