Development f optical biopsy system with fiber Raman spectroscopy in vivo measurements of biological polymers for molecular diagnosis

Yusuke Hattori, Takashi Katagiri, Gen Ichi Kanai, Yuichi Komachi, Toru Asakura, Hideo Tashiro, Hidetoshi Sato

Research output: Contribution to conferencePaperpeer-review

Abstract

In this study, in vivo Raman spectroscopy was performed originally at the epithelia of the living rat oesophagus and stomach by using a fiber-optic Raman probe and a miniaturized endoscope for small experimental animals. Since Raman spectroscopy reflects sensitively structures of biological molecules, fiber-optic Raman spectroscopy is expected to become a minimally-invasive diagnosis. The performance of our original system was evaluated by comparing between iin vivo and ex vivo Raman spectra at the rat epithelia.

Original languageEnglish
Number of pages1
Publication statusPublished - 2006 Oct 19
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: 2006 May 242006 May 26

Other

Other55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period06/5/2406/5/26

Keywords

  • Fiber-optic Raman probe
  • In vivo Raman spectroscopy
  • Optical biopsy

ASJC Scopus subject areas

  • Engineering(all)

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